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Thus, DNA methylation may act as a critical mediator, integrating environmental signals such as inflammation and oxidative stress, and ultimately influencing the gene expression pathways involved in AMD pathogenesis (Hunter et al., 2012)
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Glucose has the capability to react with the N-terminal amino group of lysine residues, forming a Schiff’s base , which can undergo rearrangements to yield fructosamines (N-(1-deoxy-D-fructos-1-yl)
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