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5.1 AMPK/SIRT1/PGC-1α and mTORC1 signaling pathways Adenosine 5′-monophosphate (AMP)-activated protein kinase [AMPK, also known as protein kinase AMP-activated alpha 1 catalytic subunit (PRKAA1)] is a central regulator of cellular energy homeostasis, activated under conditions of energy stress such as starvation or exercise (Yang et al., 2024)
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