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Here’s how the PrEP types compare: The benefits of injectable PrEP Requires only 1 dose every 2 months Slightly more effective than oral PrEP (but both are over 99% effective when taken as prescribed) The drawbacks of injectable PrEP Requires an in-person appointment for every dose Much higher cost than oral PrEP — up to 130x more expensive than generic Truvada Requires needle injection Not approved in reducing HIV risk from drug use Side effects can last longer How do I get injectable PrEP