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What may improve includes: Pain intensity and frequency Radiating symptoms (sciatica) Morning stiffness and mobility Tolerance for sitting, standing, and daily activities Sleep quality affected by pain Dependence on pain medications Many users with disc herniations report 50% to 80% improvement in symptoms while their imaging findings remain unchanged

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In particular, Fusobacterium were shown to be abundant in horses with colitis compared with healthy horses, and this genus has been associated with CD and appendicitis in humans [121]