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(PDF) Modulation of Gene Expression in Human Breast Cancer MCF7 and Prostate Cancer PC3 Cells by the Human Copper-Binding Peptide GHK-Cu.
Third, choline is essential for assembling phosphatidylcholine , the phospholipid required for VLDL formation
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This copper-binding motif is critical: the apo-peptide (GHK without copper) shows substantially reduced biological activity in most in vitro assays, indicating that the metal center is required for receptor interaction and downstream signaling
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