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For example, in muscle tissue, it forces the muscle to be more sensitive to insulin's effects, such as the decrease of fat storage [10]

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Although CTA is considered insufficient for classifying chemicals as carcinogens on its own, it is a crucial component integrated approach to testing and assessment (IATA) for non-genotoxic carcinogens (NGTxC) based on leveraging omics technology, particularly transcriptomics, to gain a more nuanced mechanistic understanding of the behavior exhibited by the tested chemical (Jacobs et al., 2016

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